Two people have been taken to hospital after a crash involving a car and a lorry.
The A4 Portway in Bristol remains closed after the collision between the junctions for Bridge Valley Road and Sylvan Way.
Avon and Somerset Constabulary were called to the scene at around 14:25 GMT.
A spokesperson for the force advised drivers to use alternative route while recovery work is carried out.
The lorry driver did not require hospital treatment, the spokesperson added.