America Ferrera and Amber Tamblyn are still best friends a decade after ‘Sisterhood of the Traveling Pants’

Soraya Roberts

Nearly ten years after "Sisterhood of the Traveling Pants" landed on screen, two of its stars are still best friends! Over the weekend, America Ferrera and Amber Tamblyn reunited at the screening of Ferrera's new film "X/Y" in Los Angeles.

"She's one of my best friends," Tamblyn told US Weekly at the event on Saturday. The 31-year-old actress added that she and husband David Cross go on double dates with Ferrera and her husband Ryan Piers Williams "all the time—to an irritating point."

"Sisterhood of the Traveling Pants," based on the young adult novel by Ann Brashares, was released in 2005 and revolved around four best friends (Ferrera, Tamblyn, Blake Lively and Alexis Bledel) who separate for the summer. To maintain their friendship, the teens share a pair of "magic" jeans that inexplicably fits them all perfectly.

The stars reunited for the film's sequel in 2008 and once again in 2013 for Entertainment Weekly.

Following the film, Ferrera made a name for herself as the star of "Ugly Betty." She subsequently became the voice of teen viking Astrid in "How to Train Your Dragon," which had its second installment earlier this year, and she is currently starring in its small-screen Cartoon Network spinoff "DreamWorks Dragons."

"We've been a part of each other's lives in really meaningful ways that go beyond making a movie together," Ferrera, 30, told EW last year of her "Sisterhood" co-stars. "We almost forget that we made a movie together because our friendship was created from so many other experiences."

Having already played the titular heroine in "Joan of Arcadia," Tamblyn went on to star on "House" and more recently joined "Two and a Half Men" as Charlie's long-lost daughter. She has also appeared on the big screen in "127 Hours" and "Django Unchained," while carving out a career as a poet.

Tamblyn and comedian David cross wed in 2012. At the wedding, Ferrera was one of three people to speak, while Lively helped the bride pick out her marigold dress.

"I feel very lucky, and it never ceases to amaze me that it turned out this way," Tamblyn told Entertainment Weekly. "And even David and Ryan are friends — like, our dudes are friends."

Meanwhile, Lively shot to fame as Serena van der Woodsen on "Gossip Girl" and starred in the 2011 blockbuster "Green Lantern."

In was on the "Lantern" set that she first met future husband, Canadian actor Ryan Reynolds. They duo wed in 2012 and unsurprisingly, all her "Sisterhood" pals were there.

"They're the most intelligent people you'll ever meet," the 26-year-old actress told Entertainment Weekly. "It's just like, Wow, how lucky am I to have those women as friends?"

Last but not least, Bledel is still known best for her role as Rory Gimore on the family drama "Gilmore Girls," a role she played from 2000 to 2007. The actress went on to star in "Sin City" and as Beth Dawes on "Mad Men," and she's currently engaged to co-star Vincent Kartheiser. The 32-year-old actress has also tread the boards in "Love Loss, and What I Wore" and "Regrets" and will next appear as Katherine Heigl's lover in the rom-com "Jenny's Wedding."

Of "Sisterhood," Bledel told EW that she was initially put off by the film's title. "Then you read it, and the characters were so well crafted and they seemed like such real people that I think we all ended up giving it a second look because of that," she said.

A third "Sisterhood" film was announced in April, which is based on Brashares' fifth and last book, "Sisterhood Everlasting." It revisits the quartet as adults, but there's no word yet on whether the original stars will return. Still, something tells us they might be open to it.