Cara Therapeutics discontinues neurological condition study as drug fails

Reuters

Updated June 12, 2024 at 5:40 p.m.

(Reuters) -Cara Therapeutics said on Wednesday it will discontinue a mid-to-late stage study for a neurological condition that causes itching after its oral drug did not show meaningful clinical benefit versus a placebo.

The company said its experimental oral version of the drug difelikefalin did not show a meaningful improvement in itching at any dose.

Notalgia paresthetica is a neurological condition that causes intense itching, burning or a tingling sensation near the shoulder blades.

(Reporting by Puyaan Singh in Bengaluru; Editing by Alan Barona and Shounak Dasgupta)

Yahoo Canada Style
'Real Housewives' star Brandi Glanville says doctors believe she has a parasite that 'jumps' around her face. What are face mites?
The 52-year-old reality star said she's spent "almost every dollar" trying to find the cause of her health issues.
BuzzFeed
You Might Be Missing These 5 Major Warning Signs Of Sleep Apnea Without Noticing
Wake up and pay attention to these red flags — even if you don’t snore.
People
Classrooms Vacated After Florida Teacher Who Tested Positive for Bacteria That Causes Legionnaires' Disease Dies
Health officials at a St. Petersburg elementary school are investigating the death of kindergarten teacher Katherine Pennington
BuzzFeed
Americans Are Sharing Their Health Insurance Horror Stories, And Something's Gotta Change
"I pay $400/ month for insurance, and they wouldn’t cover a life-saving medication."
CBC
Ontario reporting high amount of walking pneumonia, whooping cough cases
According to recent data from Public Health Ontario, there are a rising number of cases for both walking pneumonia and whooping cough. CBC’s Shannon Martin speaks to Jeffrey Pernica, a pediatric infectious disease physician at McMaster Children's Hospital to learn more.
People
8-Year-Old Cancer Survivor 'Purposely' Pushed by Bills Fan During Game Against 49ers, Family Says
Mia DeCamilla told a Buffalo news station after the incident that she doesn't plan on going back to the stadium
CBC
Canadians with cancer spend an average $33K out of pocket for medical care: report
During her cancer treatment, Vanessa Percoco felt forced to choose between paying to feel better or making rent.Percoco, 33, of Laval, Que., worked in special education and had just started on a short contract working with Grade 3 students with special needs. A diagnosis of advanced colorectal cancer in 2022 put those plans on hold.During more than two years of treatment, which included surgery to remove part of the colon as well as 12 rounds of chemotherapy, Percoco paid more than $4,000 out of
Yahoo Life UK
How to know if you’re addicted to ultra-processed foods
Is finishing a full-sized pack of crisps in one sitting normal?
Hello!
Taylor Swift's 'health risk' as she ends 18-month Eras Tour
Taylor Swift's Eras Tour ended on Sunday after 149 shows – and the musician could be at risk of ill health, caution doctors
HuffPost UK
Men With This Health Risk May Get Dementia 10 Years Earlier Than Women
Researchers discovered a decade-long discrepancy.
USA TODAY
Ham is the centerpiece of many holiday meals. Is it good for you?
Are there risks to eating ham? Here's what an expert needs you to know.
CBC
Drivers will eat cannabis gummies and take a spin in a simulator for this U of S study
A University of Saskatchewan research team is recruiting people to eat cannabis gummies and then use a state-of-the-art driving simulator. The study is designed to test impairment from THC edibles.
BBC
Daughter 'floored' by strain of caring for parents
Jennifer Owen has repeatedly asked for help in caring for her elderly parents, but to no avail.
Global News
Health Matters: New treatment for menopause
Eighty percent of women in menopause suffer from night sweats and hot flashes – and traditionally hormone therapy is the only on-label treatment available to them. But as Sarah Ryan explains in Health Matters, there’s a new prescription that’s been approved that will make treatment accessible to a wider range of women.
HuffPost
'Still Just Concepts?': NBC's Kristen Welker Presses Trump For Details On Health Care Plan
The "Meet the Press" host asked the president-elect if he has a "fully developed" plan; he promised his option would "be better" than Obamacare.
CBC
A look at Michael Garron Hospital's new pediatric outpatient centre
Toronto's Michael Garron Hospital is celebrating the grand opening of its new paediatric facility. The Child and Youth Centre is home to more than 20 clinics, including one that's midwife led. CBC’s Britnei Bilhete has the details.
The Canadian Press
How should the opioid settlements be spent? Those hit hardest often don’t have a say
People with substance use disorder across the country are not getting a formal say in how most of the approximately $50 billion in opioid lawsuit settlement money is being used to stem the crisis, a new analysis found.
CNN
Cancer-causing chemicals used in homes and workplaces banned by EPA
The US Environmental Protection Agency on Monday banned the use of two ubiquitous cancer-causing solvents that activists have been targeting for decades.
Popular Mechanics
A Single Mutation Could Send a Catastrophic Contagion From Birds to Humans
What could happen if avian flu crosses the species barrier?
Global News
Cancer costs a patient $33K, Canadian Cancer Society report says
A new Canadian Cancer Society report shows out-of-pocket costs are estimated to reach almost $33K dollars in a cancer patient's lifetime. While the health-care system covers hospital costs including chemotherapy and radiation, patients still pay for some prescription drugs and travel expenses. Katherine Ward has this story and more in Health Matters for Dec. 9, 2024.

Latest Stories