All 30 teams – 15 games – are scheduled to play on Opening Day, which would be the first time since 1968 that every team is playing its first game on the same day.
The defending World Series champion Houston Astros open the season at home against the Chicago White Sox, while other Opening Day highlights include the New York Yankees hosting the San Francisco Giants, and Cleveland Guardians visiting the Seattle Mariners.
The league introduced a new, balanced schedule for 2023 with every team playing 52 divisional games (down from 76), 46 interleague games (up from 20) and 64 intraleague games (down from 44).
Here's the full schedule for the first day of Major League Baseball's 2023 season:
2023 MLB Opening Day schedule
Atlanta Braves at Washington Nationals – 1:05 p.m. ET
San Francisco Giants at New York Yankees – 1:05 p.m
Baltimore Orioles at Boston Red Sox – 2:10 p.m.
Milwaukee Brewers at Chicago Cubs – 2:20 p.m.
Detroit Tigers at Tampa Bay Rays – 3:10 p.m.
Philadelphia Phillies at Texas Rangers – 4:05 p.m.
Pittsburgh Pirates at Cincinnati Reds – 4:10 p.m.
Colorado Rockies at San Diego Padres – 4:10 p.m.
Toronto Blue Jays at St. Louis Cardinals – 4:10 p.m.
Minnesota Twins at Kansas City Royals – 4:10 p.m.
New York Mets at Miami Marlins – 4:10 p.m.
Chicago White Sox at Houston Astros – 7:08 p.m.
Los Angeles Angels at Oakland Athletics – 10:07 p.m.
Arizona Diamondbacks at Los Angeles Dodgers – 10:10 p.m.
Cleveland Guardians at Seattle Mariners – 10:10 p.m.
This article originally appeared on USA TODAY: MLB Opening Day schedule: When does 2023 baseball season start?