There is no service on Line 3 on Saturday.
The TTC says it is closing service between Kennedy and McCowan stations for track work.
Shuttle buses are running instead.
The TTC says Ellesmere, Midland and McCowan stations will be closed, but all other stations will stay open for people to purchase tickets or load their Presto cards.
Other subway closures this weekend
Meanwhile, subway service will stop at 11 p.m. on Saturday night between Eglinton and King stations on Line 1.
On Sunday, there will be no subway service on Line 1 between Sheppard-Yonge and Bloor-Yonge stations.
Shuttle buses will be available.
The disruptions are due to automatic train control signal system testing, the TTC says.