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Witherspoon, 42, photographed with her daughter Ava, 19, and mother Betty, 70. Ava wears a Gabriela Hearst top. Levi’s jeans. Irene Neuwirth earrings. Reese wears a Marc Jacobs sweater. Effy Jewelry earrings. Fashion Editor: Tonne Goodman.

Reese Witherspoon Vogue Cover Photographed by Zoë Ghertner

Reese Witherspoon may have broken out as “America’s Sweetheart,” but in recent years she has become a powerful activist, fighting for greater representation in Hollywood for people of color, the LGBTQ community and—perhaps most of all—women. Gracing our February cover in a Givenchy green gown, the Big Little Lies star tells Vogue about her many passions, from Draper James to her storytelling brand, Hello Sunshine. In this month's slideshow, see Witherspoon dressed in Burberry, Max Mara, and Alexander McQueen as she poses alongside the powerful women in her life: her daughter, her mother, and her Time's Up collaborators.