Silence of the Lambs director Jonathan Demme dead at 73

The Oscar-winning director of the 1991 horror-thriller film The Silence of the Lambs Jonathan Demme is dead at 73.

Demme's publicist, Annalee Paulo, said Demme died Wednesday morning in his New York apartment, surrounded by his wife, director-producer Joanna, and three children, Brooklyn, Jos and Ramona.

Demme died from complications from esophageal cancer, she added.

Since his directing debut in 1971 with the film Angels Hard as They Come, Demme's storied career included directing the 1984 Talking Heads concert film Stop Making Sense, the 1988 Michelle Pfeiffer and Alec Baldwin comedy Married to the Mob and the groundbreaking 1993 Tom Hanks drama Philadelphia. 

For one of his last projects, Demme worked with Justin Timberlake for the 2016 documentary Justin Timberlake + The Tennessee Kids and was in Toronto to promote the film at TIFF.