Christina Applegate left in a 'f*** it' style depression because of her MS

Christina Applegate has been left in a deep "depression" because of her MS.

The former ‘Married With Children’ star - who was diagnosed with the neurological condition in 2021 - confessed that she is currently in a really “fatalastic, f*** it” headspace with her mental health after coming to terms with living the symptoms like mobility issues, fatigue and bowel control.

The 52-year-old actress told her friend and actress Jamie-Lynn Sigler on their podcast ‘MeSsy’: "I'm in a depression right now, which I don't think I've felt that for years. Like a real, f**** it all depression where it's kind of scaring me a little bit because it feels really fatalistic.

"I'm trapped in like this darkness right now that I haven't felt like... I don't even know how long, probably 20 something years.”

Christina also mentioned her surprise presenting stint at this year’s Primetime Emmy Awards with pal Anthony Anderson, 53, as support.

The former ‘Dead To Me’ actress told her 43-year-old pal - who also has MS - that the gig was part of “the hardest day of [her] life” and that she slept for “two days” after.

While being frank about her condition, Christina said: "This is being really honest...I don't enjoy living. I don't enjoy it. I don't enjoy things anymore."

Jamie-Lynn - who is best known for playing Tony Soprano’s daughter Meadow on the legendary HBO series ‘The Sopranos’ - admitted that she knew how “hard” it can be but found it easier to not live in the past.

She said: "It's so hard to live in a disabled body. It is so hard. I will not take that away from you and I am right there with you. But what makes it harder is when you compare it to how it used to be...Once we get you to this place where we're accepting that this is how it's going to be, maybe forever...[coping with MS] is not a reason enough for you to stop living because I sit here across from you and you still make me laugh like nobody else can. You still make me smile. You make me feel loved."

Christina first went public with her health update on X, writing: "I have been so supported by people that I know who also have this condition. It’s been a tough road. But as we all know, the road keeps going. Unless some a------ blocks it."