Summit Therapeutics cancer therapy succeeds in late-stage China study

Reuters

May 30, 2024 at 3:39 p.m.·1 min read

(Reuters) -Summit Therapeutics said on Thursday its experimental therapy to treat patients with a type of lung cancer met the main goal of a late-stage study conducted in China, sending its shares soaring 177%.

The company said its therapy showed statistically significant improvement compared to Merck's Keytruda in a head-to-head setting.

The study sponsored by Akeso showed the therapy, ivonescimab, had clinically meaningful improvement in the main goal of progression free survival compared to Keytruda.

The company was testing the therapy in patients with advanced non-small cell lung cancer, a disease in which malignant cancer cells form in the tissues of the lung.

The therapy is an antibody designed to block a protein called PD-1, which helps the body's immune system to fend off cancer.

Shares of the company more than doubled to $8.70, while those of Merck slipped 0.87%.

(Reporting by Sneha S K in Bengaluru; Editing by Arun Koyyur)

BuzzFeed
Doctors Are Explaining How A Few Common Habits Can Ultimately Lead To Serious Illnesses Like Diabetes And Heart Disease Later Down The Road
Doing this now can eventually lead to chronic anxiety, insomnia, fatigue, depression, high blood pressure, over-eating, substance abuse, and burn-out.
People
Woman Finds Out She's Pregnant 6 Months After Husband's Vasectomy, But Tests Show Procedure Was Successful (Exclusive)
Victoria and Will Wood are looking for answers as they prepare to welcome baby No. 3
Yahoo Canada Style
Céline Dion delivers emotional performance at the Paris 2024 opening ceremony — her first since cancelling tour due to Stiff Person Syndrome: Signs, symptoms & how it affected her voice
The 56-year-old Canadian singer has been experiencing symptoms of SPS for the last 17 years.
SWNS
"I was diagnosed with two rare cancers in just six weeks - it didn't feel real"
A single mum diagnosed with two rare cancers just six weeks apart had to have SIX ORGANS REMOVED - including her ovaries, uterus and cervix. Hayley Shaw, 44, previously led an active lifestyle but pelvic pain and heavy periods led to the discovery of two cancerous uterine polyps in June 2023. Hayley's world was turned upside down when she was diagnosed with a rare form of uterine cancer which typically affects women over 70. She was then told she would have an induced menopause and need a hysterectomy - preventing her from having any more children. Following her hysterectomy, Hayley - a former image consultant - returned home for a few weeks only to begin feeling unwell again.
Yahoo Canada Style
Paulina Porizkova says sex 'can get better with age' — here's how to make the most of your sex life after menopause
Porizkova, 59, says women "don’t need a steady partner, just a desire to explore" their sexuality as they age.
HuffPost
JD Vance Called For ‘Federal’ Restrictions To Traveling For Abortion In Resurfaced Clip
The GOP vice presidential candidate envisioned a post-Roe v. Wade world where “George Soros sends a 747 to Columbus to load up disproportionately Black women” to get abortions out of state.
Bloomberg
Lilly loses $120 billion in value as rival obesity drugs impress
(Bloomberg) -- Eli Lilly & Co. is down more than $120 billion in market value and its status as the poster child of the weight-loss drug frenzy is under threat with at least two rivals posting encouraging developments for their obesity treatments.Most Read from BloombergTrump Risks Losing Voters He Needs With Loaded Attacks on HarrisHarris Just Showed Why Trump Is So Afraid of HerMarkets Tear Up Popular Trades That Reached ‘Stupid Levels’Stocks Caught in Tug of War Between Tech and Rest: Markets
Yahoo Canada Style
Moderate drinking doesn't mean you'll live longer, Canadian scientists find: What to know about alcohol and cancer risk
A new analysis suggests many studies provide flawed perspectives, making light to moderate drinkers look better than they really are.
CNN
‘We cannot remain silent about what we saw.’ US doctors who volunteered in Gaza demand ceasefire in letter to White House
A group of 45 American doctors and nurses describe bloodshed in Gaza in an open letter to the White House, and demand immediate ceasefire.
CBC
P.E.I. RCMP report presence of new drug 'more potent than fentanyl'
RCMP say a dangerous synthetic opioid not found before on P.E.I. was recently seized during a drug bust in Stratford — underlining the concern that users "really don't know what they're getting."The seizure on May 28 included an envelope containing about 50 tablets."Health Canada identified the tablets as N-desethyl Isotonitazene/A-benzimidazole, a synthetic opioid said to be more potent than fentanyl," RCMP said in a news release. "Although N-desethyl Isotonitazene was reported in Nova Scotia e
Digital Spy
Coronation Street villain Rowan Cunliffe steps up blackmail plan
Coronation Street's Nick Tilsley continues being blackmailed by Rowan Cunliffe amid Leanne Battersby's involvement in The Institute.
Global News
Health Matters: Ontario has lowest ratio of registered nurses in Canada
A new report from the Canadian Institute for Health Information has found Ontario now has the lowest ratio of registered nurses in the country. Data shows the province's shortage continues to worsen, dropping to only 651 registered nurses per 100-thousand people. Katherine Ward has this story and more in Health Matters for July 26, 2024.
People
Brandi Glanville Shares Photo of Facial Disfigurement from a Skin Condition: 'I’m Miserable and Depressed'
The ‘Real Housewives of Beverly Hills’ alum showed off her swelling due to angioedema, a skin condition she was diagnosed with last year that she says is caused by stress
CNN
Texas woman’s lawsuit after being jailed on murder charge over abortion can proceed, judge rules
A Texas woman who was jailed and charged with murder after self-managing an abortion in 2022 can move forward with her lawsuit against the local sheriff and prosecutors over the case that drew national outrage before the charges were quickly dropped, a federal judge ruled Wednesday.
The Independent
Man sparks debate after refusing to share food with pregnant friend
‘Call Emma out and remind her that you repeatedly said no,’ one user on Reddit writes
WPTV- West Palm Beach Scripps
Jupiter woman one of first to receive new Alzheimer's treatment
A new drug to slow the progression of Alzheimer's disease is bringing renewed hope to patients battling the devastating diagnosis.
Hello!
I wouldn't have known I was perimenopausal if I hadn't quit drinking
Sobriety coach Christy Osborne's perimenopause symptoms were masked by drinking
The Canadian Press
Family sues after teen's 2022 death at Georgia detention center
ROME, Ga. (AP) — The family of a 16-year-old girl who died at a Georgia youth detention center in 2022 are suing over her death, contending she was denied care that would have saved her life.
Yahoo Life
More than 200,000 pounds of Boar's Head liverwurst, other deli meat recalled amid listeria outbreak. What to know about foodborne illnesses and their symptoms.
More than two dozen people have been hospitalized and two have died from a listeria outbreak linked to deli meat.
Associated Press
Daughter of Hall of Fame pitcher Dennis Eckersley on trial, accused of abandoning newborn in cold
The trial began Thursday for the daughter of baseball Hall of Fame pitcher Dennis Eckersley, who is accused of abandoning her baby after giving birth in the woods in subfreezing temperatures on Christmas night in 2022. Attorneys for Alexandra Eckersley, 27, said she didn't know she was pregnant, thought the child had died, and was suffering from substance use disorder and mental health issues. Alexandra Eckersley pleaded not guilty to charges of assault, reckless conduct, falsifying evidence and endangering the welfare of a child.

Latest Stories