Sin City will host the game for the first time next Sunday (11 February) at the Allegiant Stadium.
The venue was opened in 2020 and built at a cost of nearly $2 billion.
It has been the home of the Las Vegas Raiders for the last four seasons - but they will not be contesting the big game.
Patrick Mahomes and the Chiefs pipped the Philadelphia Eagles to secure their third Lombardi Trophy last year, and will now be looking to become the first team since the New England Patriots in 2005 to win back-to-back Super Bowls.
Standing in their way are the 49ers, led by quarterback Brock Purdy, looking to win their first title since 1995.